Alterations to the Bull Sperm Surface Proteins That Bind Sperm to Oviductal Epithelium1
نویسندگان
چکیده
منابع مشابه
Proteins from human oviductal tissue-conditioned medium modulate sperm capacitation.
BACKGROUND Spermatozoa acquire the ability to fertilize an oocyte when they become capacitated. Capacitation takes place when sperm pass through the female reproductive tract, interacting with female fluids. Both tyrosine phosphorylation of sperm proteins and the ability to respond to acrosome reaction (AR) inducers have been associated with sperm capacitation. Recent data indicate that conditi...
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In all mammalian species studied to date, sperm cells are arrested in the caudal isthmus before ovulation to form an oviductal reservoir. When ovulation occurs, discrete numbers of sperm are released from this region and ascend to the ampulla where fertilization normally occurs. Experimental evidence indicates that the sperm reservoir is instrumental in delivering the appropriate number of sper...
متن کاملEpididymosomes: transfer of fertility-modulating proteins to the sperm surface
A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation. These proteins serve roles in immunoprotection and in key steps of fertilization such as capacitation, acrosomal exocytosis and sperm-egg interactions. Their acquisition on sperm cells is mediated both by membrane vesicles (epididymosomes, EP)...
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Certain sperm components labeled with fluorescein isothiocyanate or its radioactive derivative, 125I-diiodofluorescein isothiocyanate (125IFC), are transferred at fertilization to the egg, where they persist throughout early cleavage stages at a localized site in the embryo cytoplasm (Gabel, C. A., E. M. Eddy, and B. M. Shapiro, 1979, Cell, 18:207-215; Gundersen, G. G., C. A. Gabel, and B. M. S...
متن کاملRelationship of bull fertility to sperm nuclear shape.
The relationship between sperm nuclear shape and bull fertility was determined. Two groups of bulls, 3 per group, were selected. Bulls differed in fertility based on lifetime nonreturn rates. Digital images of propidium iodide-stained sperm from each bull were collected and shape-evaluated by Fourier harmonic amplitudes 0 to 5. A discriminant function (P < .05) was constructed based on harmonic...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2012
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.112.099721